Pain that narrows your life in ways others can't see.
IV ketamine calms hypersensitized nerve pathways at the source. Clinical evidence supports use in CRPS (13 of 14 studies showed efficacy), fibromyalgia (41.5% responder rate), and neuropathic pain. Tier-based pricing at Music City Ketamine: $475-$1,425 per session depending on protocol intensity, administered by Marla Peterson, CRNA in Franklin, TN.
Chronic pain involves a phenomenon called central sensitization — the nervous system becomes hypersensitive, amplifying pain signals even when the original injury has healed. Over time, the brain and spinal cord essentially learn to stay in a heightened pain state, making everything hurt more than it should.
Ketamine blocks NMDA receptors, which are directly involved in the "wind-up" process that maintains central sensitization. It interrupts the pain signaling cascade, reduces neuroinflammation, and can essentially reset the pain processing system.
For chronic pain, dosing protocols are different from mental health infusions. Longer infusion sessions — 1 to 4 hours — are used to achieve deeper and more sustained NMDA receptor blockade. This extended protocol allows for a more thorough central sensitization reset.
At Music City Ketamine in Franklin, TN, Marla Peterson, CRNA — with 20+ years of anesthesia experience — administers every infusion in a private suite with real-time monitoring, adjusting your dose based on your specific pain condition and response.
Music City Ketamine provides a superbill that you can submit to your insurance for out-of-network reimbursement. Financing through Advance Care is also available.
Ready to explore whether ketamine therapy is right for you?
Schedule a Consultation"I've had CRPS and fibromyalgia for over eight years. I've tried every medication, every nerve block, every therapy they could think of. After my ketamine infusions with Marla, the constant burning started to quiet down. For the first time in years, I had days where the pain wasn't the first thing I thought about when I woke up."
"Marla understands chronic pain patients in a way most providers don't. She never once made me feel like I was exaggerating or drug-seeking. She listened, she explained the science, and she adjusted my infusion in real time. And Wilma curled up next to me before my session — that kind of comfort matters more than people realize."
Chronic pain protocols use longer infusion sessions — 1 to 4 hours — to achieve the central sensitization reset. Mental health infusions are typically 40-50 minutes. Marla Peterson, CRNA adjusts the protocol based on your specific condition.
Music City Ketamine in Franklin, TN provides a superbill that you can submit to your insurance for out-of-network reimbursement. Financing through Advance Care is also available.
CRPS, fibromyalgia, neuropathic pain, chronic migraines, and centralized pain syndromes have all shown positive responses to ketamine therapy in clinical research.
Certified Registered Nurse Anesthetist
20+ years of anesthesia experience. Member, Multidisciplinary Association for Psychedelic Studies (MAPS). Marla personally administers and monitors every infusion at Music City Ketamine. Read her full bio →
Common questions about IV ketamine therapy for Chronic Pain at Music City Ketamine.
Yes — clinical evidence supports IV ketamine for several chronic pain conditions. 13 of 14 studies showed efficacy for CRPS (complex regional pain syndrome), and 41.5% of fibromyalgia patients respond. It calms central sensitization at the spinal-cord and brain level.
IV ketamine has the strongest evidence for CRPS, fibromyalgia, neuropathic pain (diabetic, post-herpetic, post-surgical), chronic regional pain syndrome, and chronic post-surgical pain. Less evidence for purely nociceptive pain like arthritis.
Pain protocols are tiered by intensity. Tier 1 (1-hour, $475) for entry-level cases. Tier 2 (2-hour, $845) is most common. Severe pain (CRPS, fibromyalgia) typically uses Tier 3 (3-hour, $1,100) or Tier 4 (4-hour, $1,425) for full central sensitization reset.
Yes. IV ketamine works on NMDA receptors and central sensitization rather than opioid receptors. It does not produce opioid-like dependence and is increasingly used as an opioid-sparing or opioid-replacement strategy for chronic pain patients.
Varies widely — from weeks to months per session, depending on condition and individual response. Many chronic pain patients schedule maintenance infusions every 4-12 weeks. Each session aims to extend the relief window.
If you've exhausted the usual options and the pain is still running your life, it might be time to try a different approach. Let's talk about whether ketamine therapy at Music City Ketamine in Franklin, TN is right for you.
Schedule a Conversation Text (615) 988-4600